The real benefits of Fragment-Based Drug Discovery (FBDD) such as low entry costs and ease of generating leads can only be developed with the right high quality tool – a fragment set. It can furnish desired number of hits, at the same time remaining small in size (200 - 3 000 compounds) hence not requiring significant investment. The fragment library design is dictated by the screening technique to be employed and is done through rigorous selection of high quality compounds. Besides chemical purity, stability and solubility criteria it’s essential to pick the representatives of as many molecular clusters as possible.
Enamine’s collection of screening compounds and building blocks is known to be the largest in the world, exceeding 2.2 M substances and it can therefore yield the most diverse screening sets.
You can download SDF’s of our fragment libraries on the corresponding product pages or on the download page. Please feel free to contact us at
. We welcome cherry-picking from all libraries and can further assist your selection.